I've used to work on CS3 and now I work on the two, there's no really difference. just one important, you can't open several files or puics on a same plan. The interface is like an old version photoshop elements when you open two different files.
In fact you have to import your file in the one open to work so directly it gives you a vectorial ting you don't have any "calque" (french word). I beg everybody to work on CS3 is so fonctionnal. And for those who have an enterprise or society and who have to buy the CS to be regular in front of administration in a case of control, stay in CS3 keep your money and forget the CS4 for the moment.
Trust me, cause even if you have more brush or ting like dat in CS4, you can create your own or download other on CS3.