A female high school gym teacher in Ohio has been accused of having sex with five students over a period of five-months.

Stacy Schuler, 32, is said to have had a sexual relationship with the students, who were mostly football players, from last August to December.

Warren County jury heard the sexual acts happened off school grounds, and that the single teacher also bought alcohol for the students at Mason High School in Mason, Ohio.

Schuler, of Springboro in Dayton, Ohio, faces up to 81 years in jail if she is convicted of 16 counts of sexual battery and three offences involving an underage person.

She has been under investigation after an anonymous tip was called in to officials last month, according to a spokeswoman for the school, which has more than 3,000 students.

"I am committed to the safety and well-being of our students, and will not tolerate behaviour that does not conform to that goal," the Daily Mail quoted Principal Mindy McCarty-Stewart as saying.

"Our staff are prepared to help our students during this situation, and know how important it is to continue to build trust with our students and families," she stated.

She added the Ohio Department of Education is expected to tell the Mason Board of Education to suspend Schuler without pay. (ANI)